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Advances In Chromatography: Volume 44

For Instructors Request Inspection Copy. We provide complimentary e-inspection copies of primary textbooks to instructors considering our books for course adoption. Learn More about VitalSource Bookshelf. CPD consists of any educational activity which helps to maintain and develop knowledge, problem-solving, and technical skills with the aim to provide better health care through higher standards.

It could be through conference attendance, group discussion or directed reading to name just a few examples. We provide a free online form to document your learning and a certificate for your records. Already read this title? Please accept our apologies for any inconvenience this may cause. Exclusive web offer for individuals. Add to Wish List. Toggle navigation Additional Book Information. Description Table of Contents. Potential writers should contact the editorial office before embarking on their work and provide a synopsis to highlight what the article intends to cover.

Synopses should contain the following information. Peer review process In , RSC Advances introduced a new peer review process with a team of international associate editors to handle all of its peer review. We are committed to increasing our engagement with the research community; and working alongside a team of expert associate editors will allow us to take a significant step towards achieving this.

The team will work hand in hand with a dedicated review panel made up of specially selected expert reviewers from across all fields of the chemical sciences. All members of the reviewer panel will work within our terms of reference. Your manuscript will be assigned to an associate editor, matching its subject area to his or her knowledge and expertise. The associate editor will perform an initial assessment on the manuscript to ensure it meets the basic criteria for the journal please see the scope section.

The associate editor will solicit the expertise of one-two reviewers to assess your article and submit a report. The associate editor assigned to your work will make a decision about your manuscript based on both reports received.


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If the reports are conflicting or no clear decision can be made, another senior reviewer will be consulted. Experimental information must be provided to enable other researchers to accurately reproduce the work. Figures should include error bars where appropriate, and results should be accompanied by analyses of experimental uncertainty.

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The experimental details and the characterisation data should preferably be provided as electronic supplementary information ESI although on occasion it may be appropriate to include some or all of this within the body of the article. This will depend on the nature of the research being reported. Work that reports new methodology should be applied to existing compounds or materials that have been synthesised by a previous route, to clearly demonstrate how the new method is better than previous procedures.

It is the responsibility of the author s to provide the reviewers with the necessary information to evaluate the merit of the manuscript in terms of its scientific content. Failure to provide the necessary experimental evidence and data may result in the manuscript being withdrawn by the editor.

It is the responsibility of authors to provide fully convincing evidence for the homogeneity, purity and identity of all compounds they claim as new. This evidence is required to establish that the properties and constants reported are those of the compound with the new structure claimed. Referees will assess, as a whole, the evidence presented in support of the claims made by the authors. The requirements for characterisation criteria are detailed below. Authors are required to provide unequivocal support for the purity and assigned structure of all compounds using a combination of the following characterisation techniques: For libraries of compounds, HPLC traces should be submitted as proof of purity.

Physical Important physical properties, for example, boiling or melting point, specific rotation, refractive index, etc, including conditions and a comparison to the literature for known compounds should be provided. For crystalline compounds, the method used for recrystallization should also be documented that is, solvent etc.

Authors should provide copies of these spectra. Infrared spectra that support functional group modifications, including other diagnostic assignments should be included. High-resolution mass spectra are acceptable as proof of the molecular weight provided the purity of the sample has been accurately determined as outlined above.

The synthesis of all new compounds must be described in detail. Synthetic procedures must include the specific reagents, products and solvents and must give the amounts g, mmol, for products: For multistep synthesis papers: For a series of related compounds at least one representative procedure which outlines a specific example that is described in the text or in a table and which is representative for the other cases must be provided.

For all soluble polymers an estimation of molecular weight must be provided by a suitable method - for example, size exclusion chromatography, including details of columns, eluents and calibration standards, intrinsic viscosity, MALDI TOF, etc, in addition to full NMR characterization 1 H, 13 C as for organic compound characterization-see above. They must also include all the characterisation data for the prepared compound or material.

For a series of related compounds, at least one representative procedure which outlines a specific example that is described in the text or in a table and which is representative for the other cases, must be provided. A new chemical substance molecule or extended solid should have a homogeneous composition and structure. New chemical syntheses must unequivocally establish the purity and identity of these materials.

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Where the compound is molecular, minimum standards have been established. For manuscripts that report new compounds or materials, data must be provided to unequivocally establish the homogeneity, purity and identification of these substances. In cases where elemental analyses cannot be obtained for example, for thermally unstable compounds , justification for the omission of this data should be provided.


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  4. Note that an X-ray crystal structure is not sufficient for the characterisation of a new material, since the crystal used in this analysis does not necessarily represent the bulk sample. In rare cases, it may be possible to substitute elemental analyses with high-resolution mass spectrometric molecular weights. This is appropriate, for example, with trivial derivatives of thoroughly characterised substances or routine synthetic intermediates. Again, these may be more appropriate for the supplementary information.

    However, it should be noted that in general mass spectrometric and spectroscopic data do not constitute proof of purity, and in the absence of elemental analyses additional evidence of purity should be provided melting points, PXRD data, etc. Experimental data for new substances should also include synthetic yields, reported in terms of grams or moles, and as a percentage.

    Where the compound is an extended solid it is important to unequivocally establish the chemical structure and bulk composition. Single crystal diffraction does not determine the bulk structure. Referees will normally look to see evidence of bulk homogeneity. A fully indexed powder diffraction pattern that agrees with single crystal data may be used as evidence of a bulk homogeneous structure and chemical analysis may be used to establish purity and homogeneous composition.

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    For a series of related compounds at least one representative procedure that outlines a specific example that is described in the text or in a table and which is representative for the other cases must be provided. For nano-sized materials it is essential that the authors not only provide detailed characterisation on individual objects see above but also a comprehensive characterisation of the bulk composition. Characterisation of the bulk of the sample could require determination of the chemical composition and size distribution over large portions of the sample.

    Synthetic procedures must include the specific reagents, products and solvents, and must give the amounts g, mmol, for products: For a series of related compounds, at least one representative procedure that both outlines a specific example that is described in the text or in a table and is representative for the other cases must be provided. All nanoparticulate materials must have be purified from synthesis by-products and residual parent compounds, ions etc. If they are to be applied in dispersed form for example, as nanoparticulate drug carrier , sufficient data on the dispersion state must be provided for example, by dynamic light scattering, centrifugal analysis, nanoparticle tracking analysis.

    Authors should provide rigorous evidence for the identity and purity of the biomolecules described.

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    Purity must be established by one or more of the following:. Sequence verification also needs to be carried out for nucleic acid cases involving molecular biology. For new derivatives comprising modified monomers, the usual organic chemistry analytical requirements for the novel monomer must be provided see 'Organic compounds'. It is not however necessary to provide this level of characterisation for the oligonucleotide into which the novel monomer is incorporated. General information RSC Advances operates an article-based publishing process giving authors fast and immediate page number assignment.

    We continue to introduce new innovations, for example Proof Central — an online interface for authors to manage and submit their proof corrections easily. When the final edited and formatted version of the article is ready for publication, the article will be assigned and published with page numbers. When all articles for that issue are published, the issue is closed, with the full pagination extent added, and a new Issue in progress is started.

    With our innovative technology, readers can decide how they want to browse the issue. For both complete issues and issues in progress, articles can be ordered by the following. There will be two main indicators to show if you are viewing a complete issue or an 'Issue in Progress'. For 'Issues in Progress', the issue cover image will be the RSC Advances cover image but with the bottom right-hand corner offset from the main image as a jigsaw piece.

    In addition, after the issue number, 'Issue in Progress' will be displayed. For closed issues, the complete cover image will be shown and the full page extent displayed. Advance articles will no longer be published as these will be replaced by the publication of the final citable article with page numbers. From Volume 4, , you can view a full list of the articles in the issue ordered according to your stated preference for example, Page number, or article type etc by clicking on 'Print View' on the left-hand side underneath the issue information section. You can use the drop down menu at the top of the issue to select 'Most recently added', which will re-order the issue giving the most recently added articles at the top.

    All four ordering options pagination, article type, recently added and subject are available for complete and in-progress issues. When you sort an issue by subject, only subject areas that contain articles will be displayed. For example, if there were no articles published and assigned to the 'Analytical subject' category in that issue, then that category will not appear in the subject list for that issue. We will continue to publish web-themed collections online that appear under the 'Themed collections' tab on the journal homepage.

    Free Advances In Chromatography Volume 44 Advances In Chromatography

    You can still register and receive table of contents alerts for RSC Advances issues in the normal way. However, you can now also opt to receive subject-based e-alerts which will provide you with just a list of the articles in that issue that will be of interest to you. Once page numbers are assigned to an article these will be the final page numbers for the article. Under the new process it will not be possible to publish related articles back-to-back in an issue. All issues published in Volumes will remain as they are. RSC Advances authors will receive the proof of their article through Proof Central, a system which gives authors flexibility on how to supply their proof corrections and provides a faster, easier way to correct their article.