The Burden

Opioid abuse in the U. Published March 26, Accessed May 4, Increases in drug and opioid-involved overdose deaths—United States, PubMed Google Scholar Crossref.

Pain and Policy Studies Group. Opioid consumption motion chart. Accessed November 27, Ontario Drug Policy Research Network; British Columbia Coroners Service. January 1, March 31, British Columbia Coroners Service; The global epidemiology and burden of opioid dependence: Multiple cause of death files, Accessed March 6, Increases in drug and opioid overdose deaths—United States, Department of Information Evidence and Research. World Health Organization; Institute for Health Metrics and Evaluation.

Institute for Health Metrics and Evaluation; The state of US health, Opioid Use in the Older Adult Population. Centers for Disease Control and Prevention.

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Stephan Fihn University of Washington, Seattle. There is a risk of becoming inured to the daily barrage of news about the opioid epidemic. This article provides a sobering perspective on the enormity of the toll on the U. This is an epidemic as serious as any in this country during the past century. A recent article by Seth et al. The authors of this study do not mention the importance of distinguishing between deaths from prescription opioids and those from illegal drugs, such as heroin and illicit fentanyl, nor do they cite that as a study limitation.

It seems to me the entire limitations paragraph addresses the challenge in defining the outcome of interest, entirely consistent with the recent work of Seth et al. It is always possible to quibble with population estimates, but hard to argue with the authors' basic point. Moreover, while we the editors hold authors to a high standard in peer review, we do not require that they cite work not yet published.

Tara Gomes, PhD St.

The article by Seth et al. However, despite this, we specifically describe the limitations of the CDC Wonder data in the discussion of the manuscript.

Importantly, Seth et al. We agree with Dr.

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Kollas that undertaking such a stratification would have been interesting, had we had reliable data to do so. Finally, the intention of this manuscript was not to focus on the source of opioids, but to highlight the ongoing, and growing burden of opioid overdose on society. In our introduction, we speak to the limitations of previous work in this area which focused solely on prescription opioid overdose, and highlight that incorporating the growing role of illicit opioids into these estimates is a main impetus for this new research.

I have a rather cynical view of the "lives saved" claimed by many published research articles, like one and many others about diets, cholesterol levels, vitamins etc. Study Setting and Population. Burden of Opioid-Related Deaths. Back to top Article Information.

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Purchase access Subscribe now. Siriol Hart's review in the Times Literary Supplement of 7 December , said, " The Burden is by a writer who has been Mary Westmacott for six books and Agatha Christie for more than anyone can count. In spite of the modern smart trimmings, this seems very much the art of story-telling that would be at home in the most staunchly traditional woman's magazine, where all the problems are resolved when the mousey heroine puts on some lipstick called, in this case "Fatal Apple" , and finds the love of her life.

Vernon Johnson reviewed the novel in the 20 November , issue of The Guardian when he called it a "fantastical novelette" and quoted several lines from the book in a disparaging fashion, stating that they were examples of "the style and the treatment". From Wikipedia, the free encyclopedia. This article is about the Agatha Christie novel. For the Swedish animated film, see The Burden film. Works by Agatha Christie. Retrieved from " https: Novels by Agatha Christie British novels Works published under a pseudonym Heinemann publisher books.

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